Chang-Gyu Hahn

This study shows that blocking the Src-PSD-95 interaction with a peptide rescues NMDAR hypofunction and improves behavioral deficits in schizophrenia models.

The paper identifies population-level variation in enhancer expression in the human brain and links enhancer eQTL to schizophrenia heritability.

The paper identifies acetylated chromatin domains associated with dysfunction in schizophrenia and bipolar disorder by analyzing histone modifications in prefrontal cortex samples.

This paper performs a large-scale eQTL meta-analysis across cerebral cortical and cerebellar brain regions, identifying distinct eQTL patterns and demonstrating improved power over existing studies.

The paper functionally annotates rare structural variants in the human brain by integrating SV calling with RNA-seq data to assess their regulatory effects and prioritize pathogenic deletions.

The paper identifies lamina-specific gene expression changes in pyramidal neurons from schizophrenia patients compared to controls, highlighting immune and synaptic pathway disruptions.

The paper analyzes allelic expression bias in schizophrenia using RNA-seq data to assess imprinted gene expression and its relationship with age, ancestry, and disease.