Toni Mueller

This study investigates whether enhancing cathepsin D or disrupting ZKSCAN3 in the CNS can reduce α-synuclein aggregation and dopaminergic neurodegeneration, but finds no significant effect.

The paper examines protein expression levels of prenyltransferase subunits in schizophrenia patients and finds decreased expression of FNTA, PGGT1B, and RABGGTB in the dorsolateral prefrontal cortex.

The paper investigates protein expression levels of galactose and N-acetylgalactosamine transferases in schizophrenia brain tissue and identifies reduced B4GALT1 and GALNT16.

The paper finds increased ST8SIA2 protein expression in schizophrenia superior temporal gyrus, suggesting a potential compensatory mechanism for impaired PSA-NCAM synthesis.

The paper identifies dysregulated mRNA expression of 36 glycosylation enzymes in schizophrenia patients, suggesting disrupted glycosylation pathways contribute to the disorder.