BiochemistrybioRxivPreprint
Fubylation as a Druggable Ubiquitin-Like Conjugation System Controlling Hippo Pathway Activity
Maya L. Bulos, Edyta M. Grzelak, Kayla Nutsch…·Michael J. Bollong
This study identifies sCMF231, a small molecule that activates YAP by inhibiting FUBI-mediated fubylation of Annexin A2, thereby enhancing YAP transcriptional activity.
DOI 10.1101/2025.07.06.663376