Sodium valproate increases activity of the sirtuin pathway resulting in beneficialeffects for spinocerebellar ataxia-3 in vivo
Maxinne Watchon, Luan Luu, Katherine J. Robinson, Kristy C. Yuan, Alana De Luca, Hannah J. Suddull, Madelaine C. Tym, Gilles J. Guillemin, Nicholas James Cole, Garth A. Nicholson, Roger S. Chung, Albert Lee, Angela S. Laird
The paper shows sodium valproate activates the sirtuin pathway, improving movement in a zebrafish model of spinocerebellar ataxia-3.
Molecular Brain · Aug 20, 2021Peer-reviewedNeuroscience