Author

Gilles J. Guillemin

Macquarie UniversityORCID 0000-0001-8105-4470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Benjamin HengiD· 2 shared Abid BhatiD· 1 shared Alana De LucaiD· 1 shared Albert LeeiD· 1 shared Angela S. LairdiD· 1 shared Bruce James BrewiD· 1 shared C. JagadishiD· 1 shared Christopher Peter MarquisiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioinformatics

Benjamin HengORCID

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Author profile →

3 papers

Recent·Most cited

BioinformaticsScientific ReportsPeer-reviewedJun 12, 2024

Visualization of Incrementally Learned Projection Trajectories for Longitudinal Data

Tamasha Malepathirana, Damith Senanayake, Vini Gautam…·Saman Kumara Halgamuge

The paper introduces IL-VIS, a machine learning pipeline that incrementally learns and visualizes progression trajectories for longitudinal data, demonstrating its utility on brain organoid electrophysiological data.

5 citations

electronic health recordsmachine learning (classical)

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NeuroscienceMolecular BrainPeer-reviewedAug 20, 2021

Sodium valproate increases activity of the sirtuin pathway resulting in beneficialeffects for spinocerebellar ataxia-3 in vivo

Maxinne Watchon, Luan Luu, Katherine J. Robinson…·Angela S. Laird

The paper shows sodium valproate activates the sirtuin pathway, improving movement in a zebrafish model of spinocerebellar ataxia-3.

17 citations

zebrafishproteomics

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NeurosciencebioRxivPreprintDec 4, 2020

Inhibition of phosphodiesterase - 10A by Papaverine protects human cortical neurons from quinolinic acid-induced oxidative stress and synaptic proteins alterations

Abid Bhat, Vanessa X. Tan, Benjamin Heng…·Gilles J. Guillemin

This study shows that papaverine inhibits PDE10A, reducing oxidative stress and protecting synaptic proteins in human cortical neurons exposed to quinolinic acid.

DOI 10.1101/2020.12.04.411868

humanstatistical model

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