Author

Jacob Smith

University of Wisconsin–MadisonORCID 0000-0002-3056-2237Unclaimed ORCID profile · follow to get notified of new preprints

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Jacob Smith2 papers · Dalhousie University

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Barak BlumiD· 1 shared Bayley J. WatersiD· 1 shared Cyrus R. Sethna· 1 shared Julia Lemanski· 1 shared Maria Del Carmen Mendoza Niemes· 1 shared Matthew R. Wagner· 1 shared Nicolas G Pintozzi· 1 shared Sutichot D. NimkulratiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Barak BlumORCID

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1 paper

Recent·Most cited

Developmental BiologybioRxivPreprintMar 16, 2026

Genome-wide cell type-specific and sex-specific transcriptional dysregulation in the islet of Langerhans underlies islet dysfunction in Down syndrome-related diabetes

Cyrus R. Sethna, Maria Del Carmen Mendoza Niemes, Bayley J. Waters…·Barak Blum

The paper identifies cell type-specific and sex-specific transcriptional dysregulation in islets of Langerhans in Down syndrome mice, linking it to increased T2D risk.

DOI 10.64898/2026.03.12.711435