GenomicsMitochondrionPeer-reviewed
Long read mitochondrial genome sequencing using Cas9-guided adaptor ligation
Amy R. Vandiver, Brittany Pielstick, Timothy Gilpatrick…·Winston Timp
This paper introduces a method to sequence mtDNA using Cas9-guided adaptor ligation and nanopore long reads, enabling mutation phasing and detection of age-induced deletions in a patient with mtDNA-linked syndrome.
30 citations