Author

Jérôme Ausseil

Centre National de la Recherche ScientifiqueORCID 0000-0002-3059-9777Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adeline ChaubetiD· 1 shared Alexei GorelikiD· 1 shared Alexey V. PshezhetskyiD· 1 shared Angelo PalmigianoiD· 1 shared Bénédicte AmilhoniD· 1 shared Bhushan NagariD· 1 shared Brian BiggeriD· 1 shared Chloé DiasiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adeline ChaubetORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Clinical InvestigationPeer-reviewedJun 17, 2025

Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins

TianMeng Xu, Rachel Heon‐Roberts, Travis Moore…·Alexey V. Pshezhetsky

This study shows that reduced NEU1 activity in neurological MPS leads to hypersialylation of brain glycoproteins, contributing to CNS pathology through disrupted synaptogenesis and behavior.

5 citations

humanmouse

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NeuroscienceMolecular MedicinePeer-reviewedNov 4, 2024

Extracellular vesicles from microglial cells activated by abnormal heparan sulfate oligosaccharides from Sanfilippo patients impair neuronal dendritic arborization

Chloé Dias, Nissrine Ballout, Guillaume Morla…·Stéphanie Trudel

This paper shows that abnormal heparan sulfate oligosaccharides from MPS III patients activate microglia to secrete EVs that impair neuronal dendritic arborization.

3 citations

humanproteomics

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