Ping Fu

The paper shows how N-terminal pyroglutamylation (pQ) biases GPCR activation by altering ligand conformation and receptor pocket mechanics, enabling subtype-selective signaling in both Aplysia and human systems.

This study identifies 5,053 novel virus long non-coding RNAs (vlncRNAs) across 25 viral species and finds that many structurally mimic host lncRNAs, potentially acting as miRNA sponges.

This paper introduces FluRisk, a computational framework using genomic data and AI to assess the risk of emerging influenza viruses, showing improved performance over traditional methods.

VIGA is a tool for eukaryotic virus identification and genome assembly from NGS data, showing improved performance in assembling complete genomes and revealing virome differences in disease states.

vsRNAfinder identifies high-confidence viral small RNAs from sRNA-Seq data, outperforming existing methods in sensitivity.