Cell BiologyMolecular OncologyPeer-reviewed
Paclitaxel induces NM2-dependent cellular contraction through GEF-H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells
Gloria Asensio-Juárez, Rafael Perez-Diaz, Hugo Ramos-Solano…·Miguel Vicente‐Manzanares
This study shows paclitaxel induces cancer cell contraction via GEF-H1 dissociation from microtubules and RhoA/ROCK activation, with tubulin acetylation regulating this process.