Author

Taylor L. Sheehy

Vanderbilt UniversityORCID 0000-0002-3100-8115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Blaise R. KimmeliD· 2 shared Jacob A. SchulmaniD· 2 shared John T. WilsoniD· 2 shared Karan AroraiD· 2 shared Alexander J. KwiatkowskiiD· 1 shared Alissa M. WeaveriD· 1 shared Caitlin McAteeiD· 1 shared Katherine Nicole Gibson-CorleyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

Blaise R. KimmelORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Macromolecular Diamidobenzimidazole Conjugates Activate STING

Karan Arora, Taylor L. Sheehy, Jacob A. Schulman, Blaise R. Kimmel, Caitlin McAtee, Vijaya Bharti, Alissa M. Weaver, John T. Wilson

This study shows that macromolecular diABZI conjugates activate STING in vitro and in vivo, with similar potency to small molecule agonists, suggesting new strategies for STING agonist delivery.

bioRxiv · Jan 21, 2025 · PreprintBioengineering

STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy

Taylor L. Sheehy, Alexander J. Kwiatkowski, Karan Arora, Blaise R. Kimmel, Jacob A. Schulman, Katherine Nicole Gibson-Corley, John T. Wilson

This paper develops SAPCon, a polymer-drug conjugate that activates the STING pathway in tumors, enhancing immunotherapy efficacy by promoting an immunogenic microenvironment and improving tumor growth inhibition.

ACS Central Science · Aug 20, 2024Peer-reviewedBioengineering