Author

John T. Wilson

Vanderbilt UniversityORCID 0000-0002-9144-2634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Blaise R. KimmeliD· 2 shared Jacob A. SchulmaniD· 2 shared Karan AroraiD· 2 shared Taylor L. SheehyiD· 2 shared Alexander J. KwiatkowskiiD· 1 shared Alissa M. WeaveriD· 1 shared Caitlin McAteeiD· 1 shared Katherine Nicole Gibson-CorleyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

Blaise R. KimmelORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJan 21, 2025

Macromolecular Diamidobenzimidazole Conjugates Activate STING

Karan Arora, Taylor L. Sheehy, Jacob A. Schulman…·John T. Wilson

This study shows that macromolecular diABZI conjugates activate STING in vitro and in vivo, with similar potency to small molecule agonists, suggesting new strategies for STING agonist delivery.

DOI 10.1101/2025.01.21.634206

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringACS Central SciencePeer-reviewedAug 20, 2024

STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy

Taylor L. Sheehy, Alexander J. Kwiatkowski, Karan Arora…·John T. Wilson

This paper develops SAPCon, a polymer-drug conjugate that activates the STING pathway in tumors, enhancing immunotherapy efficacy by promoting an immunogenic microenvironment and improving tumor growth inhibition.

40 citationstop 3%

mouseexperimental assay

𝕏 PostBluesky