BiophysicsNature CommunicationsPeer-reviewed
Structural basis of apoptosis induction by the mitochondrial voltage dependent anion channel
Melina Daniilidis, Umut Günsel, George Broutzakis…·Franz Hagn
This study reveals how VDAC1 oligomerization triggers apoptosis by exposing its N-terminal helix, which neutralizes anti-apoptotic BclxL and promotes pore formation by Bak.
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