NeurosciencebioRxivPreprint
Acid sphingomyelinase deactivation post-ischemia/ reperfusion promotes cerebral angiogenesis and brain remodeling via small extracellular vesicles
Ayan Mohamud Yusuf, Nina Hagemann, Xuejing Zhang…·Dirk Matthias Hermann
The paper shows that antidepressants inhibit acid sphingomyelinase, reducing brain damage after ischemia/reperfusion and promoting angiogenesis via exosome release.
DOI 10.1101/2021.03.01.433387