Bernd Giebel

The paper develops a third-generation lentiviral vector system for flow virometry to analyze viral envelope proteins, demonstrating its ability to detect antibody binding to different viral surface proteins.

This study shows that hyperlipidemia reduces the neuroprotective effects of MSC-derived extracellular vesicles, but DNase-I treatment restores their efficacy by rebalancing immune responses.

This study shows that monocytes are essential for the neuroprotective effects of MSC-EVs in stroke, as their depletion negates these benefits and leads to immune system dysregulation.

This study shows that neutralizing extracellular histones reduces secondary brain injury and improves recovery after ischemic stroke complicated by pneumonia.

This paper introduces a deep learning model to identify virus-infected cells from light microscopy images without using labels or stains, achieving up to 96% classification accuracy.

The paper introduces TeLEV, a method to track EV proteomes in immune cells, revealing EV-driven immunomodulation through STAT5-dependent mechanisms.

This paper demonstrates that lipid nanoparticle-delivered miR-187 reduces inflammation and improves cardiac function in sepsis models.

This study evaluates the therapeutic effects of hiEVs from different media in an OA mouse model, finding that xeno-free hiEVs reduce joint damage and promote cartilage repair.

This study shows tumor-derived extracellular vesicles containing serpins A1/A3 reprogram neutrophils to support tumor growth by extending their lifespan and suppressing CD8 T cells.

The paper quantifies circulating extracellular vesicles (EVs) in healthy humans, showing high inter-individual variability and identifying platelets as the main source of tetraspanin+ EVs.

The paper identifies VAMP5 as a SNARE component in extracellular vesicles released by retinal Muller glia and shows differences in their secretomes compared to neurons.

This study evaluates fluorescent dyes for labelling MSC-EV preparations, finding Exoria as the only specific dye and highlighting the need for better EV characterization tools.

The paper shows that antidepressants inhibit acid sphingomyelinase, reducing brain damage after ischemia/reperfusion and promoting angiogenesis via exosome release.