Author

Thomas J. Kucharski

McGill UniversityORCID 0000-0002-3127-5352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bhushan NagariD· 1 shared Ivan TopisirovićiD· 1 shared Jerry PelletieriD· 1 shared Jose G. TeodoroiD· 1 shared Mohamed Moustafa-KamaliD· 1 shared Susanne BechstedtiD· 1 shared Tatiana LyalinaiD· 1 shared Valentina GandiniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Bhushan NagarORCID

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2 papers

Recent·Most cited

An Aurora Kinase A/TPX2 complex phosphorylates CKAP2 to control mitotic spindle growth

Thomas J. Kucharski, Tatiana Lyalina, Susanne Bechstedt

The paper identifies Aurora A/TPX2 as CKAP2 interactors and shows Aurora A phosphorylates CKAP2, reducing its microtubule affinity and affecting spindle growth.

bioRxiv · Sep 9, 2025 · PreprintBiochemistry

The mTORC1/S6K/PDCD4/eIF4A axis determines outcome of mitosis.

Mohamed Moustafa-Kamal, Thomas J. Kucharski, Wissal El-Assaad, Yazan M. Abbas, Valentina Gandin, Bhushan Nagar, Jerry Pelletier, Ivan Topisirović, Jose G. Teodoro

The paper identifies the mTORC1/S6K/PDCD4/eIF4A axis as critical for determining cell fate during mitotic arrest, showing that disrupting this pathway can enhance the effectiveness of anti-mitotic drugs.

Cell Reports · Oct 1, 2020Peer-reviewedMolecular Biology