Valentina Gandin

This study uses single-particle tracking to show that ARC/ARG3.1 protein shuttles between cytoplasmic clusters and the nucleus in response to synaptic activation.

This paper introduces cycleHCR technology for high-resolution spatial transcriptomics and protein imaging in thick tissues, demonstrating its application in mouse embryos and brain slices.

The paper investigates how 3D genome organization, specifically through Cohesin, influences gene co-expression in single cells and reveals its role in maintaining long-range chromatin interactions.

The paper identifies the mTORC1/S6K/PDCD4/eIF4A axis as critical for determining cell fate during mitotic arrest, showing that disrupting this pathway can enhance the effectiveness of anti-mitotic drugs.

The paper introduces anota2seq, an algorithm for analyzing translational efficiency from ribosome or polysome profiling data, revealing translational buffering and mTOR-dependent gene regulation.