Identification of cysteine metabolism regulator (CymR)-derived pentapeptides as nanomolar inhibitors of Staphylococcus aureus O-acetyl-ʟ-serine sulfhydrylase (CysK)
Jordan L. Pederick, Bethiney C. Vandborg, Amir George, Hannah Bovermann, Jeffrey M. Boyd, Joel S. Freundlich, John B. Bruning
This paper identifies CymR-derived pentapeptides as nanomolar inhibitors of SaCysK, showing higher potency than CysE-derived peptides.
ACS Infectious Diseases · Dec 20, 2024Peer-reviewedBiochemistry