Jordan L. Pederick

This study characterizes the structure and catalytic mechanism of AfuCys1a, identifies potential inhibitors, and aims to combat antifungal drug resistance in Aspergillus fumigatus.

The paper identifies a ternary switch in ERα LBD that regulates receptor activity through distinct H12 conformations, revealing an apo state and its destabilization by mutations.

This paper identifies CymR-derived pentapeptides as nanomolar inhibitors of SaCysK, showing higher potency than CysE-derived peptides.

This study analyzes the structural evolution of estrogen receptor regulatory domains, revealing conserved network structures and their implications for breast cancer and reproductive disorders.