Author

Reinier de Vries

Max Planck SocietyORCID 0000-0002-3143-6830Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Organism:multiple species· 1

Frequent Co-Authors

Bert L. de GrootiD· 3 shared Wojciech KopećiD· 3 shared Adam LangeiD· 1 shared Carl ÖsteriD· 1 shared Chaowei ShiiD· 1 shared Chen FaniD· 1 shared Chenggong HuiiD· 1 shared Crina M. NimigeaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

Bert L. de GrootORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hydrophobic and lipid-mediated gating mechanism revealed by low-conductance MthK mutants

Reinier de Vries, Hee-Seop Yoo, Chen Fan, Wojciech Kopeć, Crina M. Nimigean, Bert L. de Groot

This study investigates the gating mechanism of MthK channels using mutants, revealing hydrophobic and lipid-mediated processes that drive channel closure.

bioRxiv · Apr 30, 2026 · PreprintBiophysics

Atomistic Mechanism of Calcium-Mediated Inward Rectification of the MthK Potassium Channel by Solid-State NMR and MD Simulations

Carl Öster, Reinier de Vries, Juan Li, Denis Qoraj, Sascha Lange, Chaowei Shi, Wojciech Kopeć, Bert L. de Groot, Adam Lange

This study identifies a calcium-mediated gating mechanism in the MthK potassium channel using solid-state NMR and MD simulations, revealing how Ca2+ blocks outward K+ flow while allowing inward flow.

Journal of the American Chemical Society · Dec 1, 2025Peer-reviewedBiophysics

Effective Polarization in Potassium Channel Simulations: Ion Conductance, Occupancy, Voltage Response, and Selectivity

Chenggong Hui, Reinier de Vries, Wojciech Kopeć, Bert L. de Groot

This paper improves molecular dynamics simulations of potassium channels by incorporating polarization effects, achieving accurate predictions of conductance, ion occupancy, voltage response, and selectivity.

Proceedings of the National Academy of Sciences · May 20, 2025Peer-reviewedBiophysics