Author

Cristina M. Risi

Old Dominion UniversityORCID 0000-0002-3145-2072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein structure prediction· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Vitold E. GalkiniD· 2 shared Alla S. KostyukovaiD· 1 shared Betty BelknapiD· 1 shared Carol C. GregorioiD· 1 shared Howard D. WhiteiD· 1 shared Jose R. PintoiD· 1 shared Prescott Bryant ChaseiD· 1 shared Tania M. LarrinagaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

Vitold E. GalkinORCID

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2 papers

Recent·Most cited

The structure of the native cardiac crossbridge in the rigor state.

Cristina M. Risi, Tyler M. Nguyen, Betty Belknap, Howard D. White, Jose R. Pinto, Prescott Bryant Chase, Vitold E. Galkin

This study reports the high-resolution structure of the native cardiac rigor cross-bridge, revealing how myosin heads and thin filament components coordinate during contraction.

Science Advances · Aug 26, 2026Peer-reviewedBiophysics

Structure of the Leiomodin-2 Regulated Actin Filament Pointed End Assembly from Profilactin

Cristina M. Risi, Tania M. Larrinaga, Alla S. Kostyukova, Carol C. Gregorio, Vitold E. Galkin

This study uses cryo-EM to reveal how Lmod2 stabilizes actin subunits at the pointed end of filaments and promotes elongation by introducing strain.

bioRxiv · May 18, 2026 · PreprintBiophysics