Author

Carol C. Gregorio

Icahn School of Medicine at Mount SinaiORCID 0000-0002-0044-2074Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Tania M. LarrinagaiD· 2 shared Alla S. KostyukovaiD· 1 shared Benoit G. BruneauiD· 1 shared Christine E. SeidmaniD· 1 shared Cristina M. RisiiD· 1 shared Danos C. Christodoulou· 1 shared Dario Miguel-Perez· 1 shared Janet RossantiD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Tania M. LarrinagaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure of the Leiomodin-2 Regulated Actin Filament Pointed End Assembly from Profilactin

Cristina M. Risi, Tania M. Larrinaga, Alla S. Kostyukova, Carol C. Gregorio, Vitold E. Galkin

This study uses cryo-EM to reveal how Lmod2 stabilizes actin subunits at the pointed end of filaments and promotes elongation by introducing strain.

bioRxiv · May 18, 2026 · PreprintBiophysics

Leiomodin 2 functions as a processive pointed-end elongator of actin filaments

Sudipta Biswas, Tania M. Larrinaga, Sandeep Choubey, Carol C. Gregorio, Shashank Shekhar

This study identifies Leiomodin 2 as a processive actin polymerase that elongates pointed ends of actin filaments, linking its dysfunction to dilated cardiomyopathy.

bioRxiv · May 7, 2026 · PreprintBiochemistry

Cardiac enriched BAF chromatin remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

Xin Sun, Swetansu K. Hota, Yu-Qing Zhou, Stefanie Mares Novak, Dario Miguel-Perez, Danos C. Christodoulou, Christine E. Seidman, Jonathan G. Seidman, Carol C. Gregorio, R. Mark Henkelman, Janet Rossant, Benoit G. Bruneau

This study shows that Baf60c regulates gene expression programs critical for heart development and function by interacting with Myocardin and controlling contractile proteins and metabolic genes.

Biology Open · Jan 1, 2017Peer-reviewedDevelopmental Biology