Cooption of antagonistic RNA-binding proteins establishes cell hierarchy in Drosophila neuro-developmental tumors
Sara Genovese, Raphaël Clément, Cassandra Gaultier, Florence Besse, Karine Narbonne-Reveau, Fabrice Daian, Sophie Foppolo, Nuno Miguel Luis, Cédric Maurange
This study identifies how the antagonistic RNA-binding proteins Imp and Syncrip drive tumor hierarchy in Drosophila neuro-developmental tumors through deregulated transitions during development.
eLife · Sep 30, 2019Peer-reviewedDevelopmental Biology