Cédric Maurange

The paper shows MYCN overexpression in avian embryos leads to SHH medulloblastoma-like tumors through a three-step process involving ATOH1+ progenitors and PAX6 reprogramming.

This study identifies a local regulatory mechanism that drives spatial segregation of cancer stem cells in tumors and shows how it constrains their differentiation dynamics.

The paper investigates how tumour growth in a Drosophila brain cancer model is influenced by host tissue resistance through cell competition and JNK pathway dynamics.

The paper introduces AGO-APP to isolate active miRNAs from Drosophila neural cells, identifies a miRNA module controlling neuroblast to neuron transition, and shows their cooperative function.

This study identifies a conserved role of serotonin signaling in regulating actomyosin contractility during morphogenesis across Drosophila and chicken embryos.

This study identifies how the antagonistic RNA-binding proteins Imp and Syncrip drive tumor hierarchy in Drosophila neuro-developmental tumors through deregulated transitions during development.

The paper shows that chinmo is silenced in Drosophila neuroblasts and neuroepithelial cells through different mechanisms to regulate self-renewal.