Nuno Miguel Luis

This study shows microtubules coordinate mitochondria transport and myofibril formation during muscle development in Drosophila and mammals.

The paper identifies a titin-dependent biomechanical feedback mechanism that adjusts sarcomere structure to meet the functional demands of different insect muscle types.

The paper develops a nanobody toolbox to study the localization and dynamics of Drosophila titin homologs in muscle sarcomeres, revealing structural insights and demonstrating nanobodies' utility in vivo.

The paper shows that myofibril and mitochondria morphogenesis in Drosophila muscles are coordinated by a biomechanical feedback mechanism involving spalt and mitochondrial dynamics.

This study identifies the Hippo pathway's role in regulating sarcomeric gene expression to control myofibril assembly and muscle fiber growth in Drosophila.

This study identifies how the antagonistic RNA-binding proteins Imp and Syncrip drive tumor hierarchy in Drosophila neuro-developmental tumors through deregulated transitions during development.