Author
Åbo Akademi UniversityORCID 0000-0002-3184-3938Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Mirva Pääkkönen, Iris Purma, Johannes A. M. Merilahti, Otto Kauko
The paper introduces DASH-PISA, a method for automated thermal proteome profiling that enables high-throughput compound screening by improving efficiency and reducing costs.
Adam Zeiner, Julia Krasensky-Wrzaczek, Sunita Jindal…·Michael Wrzaczek
This study shows CRK2 regulates plant development by modulating callose synthase activity, affecting symplastic transport and leading to starch accumulation and growth defects in Arabidopsis.
Sunita Jindal, Adam Zeiner, Alexey Bondar…·Michael Wrzaczek
This study shows CRK2 phosphorylates and sequesters QSK1 at the plasma membrane, preventing callose deposition at plasmodesmata under normal conditions, and its dephosphorylation allows QSK1 relocalization during osmotic stress.
Huiyan Ying, Weikaixin Kong, Aron Schulman…·Mitro Miihkinen
The paper develops an ML-powered drug discovery pipeline to design selective CK2 inhibitors with favorable off-target profiles, achieving a 90% hit-rate.
Jie Bao, Sanna Pikkusaari, Jun Dai…·Jing Ping Tang
This study identifies BX-912 as a therapeutic agent for ovarian serous carcinoma, revealing HES1 as a target and showing synergistic effects with olaparib.