Adam Kim

This study identifies 4-hydroxyphenylacetic acid (4-HPAA) as a microbial metabolite that enhances interferon signaling and suppresses NF-κB inflammation, reducing alcohol-induced liver injury and lipid accumulation.

This paper describes a protocol using MetVAE to construct molecular networks from metabolomics data, identifying lipid correlations in a mouse model.

This study examines how aging affects immune and periosteal responses to fracture in mice, finding reduced proliferative capacity of periosteal stem/progenitor cells and increased CD8+ T cell recruitment in aged mice.

The paper uses Hi-C and scRNA-seq to analyze chromatin structure and gene expression in monocytes from alcohol-associated hepatitis patients, finding altered genome organization affecting immune gene expression.