Author

Yui Chun S. Wan

Duke UniversityORCID 0000-0002-3189-0021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:electrophysiology· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Gowthami M. ArepallyiD· 2 shared Huanghe YangiD· 2 shared Marilyn J. TeleniD· 2 shared Martha D. Delahunty· 2 shared Sanjay KhandelwaliD· 2 shared Grace LeeiD· 1 shared Ke Zoe Shan· 1 shared Pengfei LiangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

Gowthami M. ArepallyORCID

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2 papers

Recent·Most cited

PhysiologyBlood Red Cells & IronPeer-reviewedOct 6, 2026

Gardos potassium channel amplifies PIEZO1-TMEM16F coupling in red blood cells

Yui Chun Serena Wan, Martha D. Delahunty, Grace Lee…·Huanghe Yang

The paper identifies Gardos as an amplifier of PIEZO1-TMEM16F signaling in red blood cells, enhancing Ca2+ entry and PS externalization, and suggests it as a therapeutic target for diseases like sickle cell disease.

DOI 10.1016/j.brci.2026.100140

humanelectrophysiology

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Pharmacology & ToxicologybioRxivPreprintJan 24, 2026

Cannabidiol Inhibits PIEZO Channels to Mitigate Red Blood Disorders

Pengfei Liang, Yui Chun S. Wan, Ke Zoe Shan…·Huanghe Yang

This paper shows that cannabidiol inhibits PIEZO channels in red blood cells, reducing calcium overload and related pathologies in hereditary xerocytosis and sickle cell disease.

2 citations

humanmouse

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