Author

Gary C. H. Mo

University of Illinois ChicagoORCID 0000-0002-3191-2155Unclaimed ORCID profile · follow to get notified of new preprints

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Asrar B. MalikiD· 1 shared Chinnaswamy TiruppathìiD· 1 shared Hui Chen· 1 shared Lasanthi Jayathilaka· 1 shared Mohammad Owais AnsariiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Asrar B. MalikORCID

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1 paper

Recent·Most cited

Ubiquitin ligase CHFR impairs Tie2 signaling via K48-linked ubiquitylation and degradation of Akt1 in endothelial cells

Mohammad Owais Ansari, Gary C. H. Mo, Lasanthi Jayathilaka, Hui Chen, Asrar B. Malik, Chinnaswamy Tiruppathì

This study identifies CHFR as a regulator of endothelial inflammatory responses by promoting Akt1 ubiquitylation and degradation, thereby impairing Tie2 signaling and endothelial barrier integrity.

bioRxiv · Mar 31, 2026 · PreprintCell Biology