NeuroscienceNeuropsychopharmacologyPeer-reviewed
mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder.
Antonia Gurgone, Riccardo Pizzo, Alessandra Raspanti…·Maurizio Giustetto
This study shows that mGluR5 positive-allosteric modulators correct synaptic and behavioural defects in a CDKL5 deficiency disorder mouse model and human patients.
16 citations