MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo
Erol Can Bayraktar, Lou Baudrier, Ceren Özerdem, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Andrew L. Cangelosi, David M. Sabatini, Kıvanç Birsoy, Walter W. Chen
The paper introduces MITO-Tag Mice to isolate mitochondria from specific cell types in vivo and identifies mitochondrial metabolite changes during fasting and refeeding in hepatocytes.
Proceedings of the National Academy of Sciences · Dec 12, 2018Peer-reviewedMolecular Biology