Author

Walter W. Chen

Broad InstituteORCID 0000-0002-7752-9581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alexandros Zografakis· 1 shared Ana G. PedrosaiD· 1 shared Ana Rita SilvaiD· 1 shared Andrew L. CangelosiiD· 1 shared Bernardo Nunes-Silva· 1 shared Bettina WarscheidiD· 1 shared Caroline A. LewisiD· 1 shared Ceren ÖzerdemiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Alexandros Zografakis

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2 papers

Recent·Most cited

PEX39 facilitates the peroxisomal import of PTS2 proteins

Walter W. Chen, Tony A. Rodrigues, Daniel Wendscheck, Ana G. Pedrosa, Chendong Yang, Tânia Francisco, Till Möcklinghoff, Alexandros Zografakis, Bernardo Nunes-Silva, Reut Ester Avraham, Ana Rita Silva, Maria J. Ferreira, Hirak Jyoti Das, Janet Koster, Simone Neuwirth, , Bettina Warscheid

This study identifies PEX39 as a cytosolic peroxin that facilitates PTS2-protein import by interacting with PEX7 and stabilizing its binding to cargo.

Nature Cell Biology · Jul 30, 2025Peer-reviewedCell Biology

MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

Erol Can Bayraktar, Lou Baudrier, Ceren Özerdem, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Andrew L. Cangelosi, David M. Sabatini, Kıvanç Birsoy, Walter W. Chen

The paper introduces MITO-Tag Mice to isolate mitochondria from specific cell types in vivo and identifies mitochondrial metabolite changes during fasting and refeeding in hepatocytes.

Proceedings of the National Academy of Sciences · Dec 12, 2018Peer-reviewedMolecular Biology