PPARγ activation by lipolysis-generated ligands is required for cAMP dependent UCP1 induction in human thermogenic adipocytes
Anand Desai, Zinger Yang Loureiro, Tiffany DeSouza…·Silvia Corvera
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University of Massachusetts Chan Medical SchoolORCID 0000-0002-3238-485XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Anand Desai, Zinger Yang Loureiro, Tiffany DeSouza…·Silvia Corvera
Zinger Yang, Amruta Samant, Anand Desai…·Tammy Nguyen
The paper identifies bone marrow adipose tissue as a hematopoietic niche that drives pro-inflammatory monocyte production via leptin signaling during aging.
Javier Solivan-Rivera, Zinger Yang, Tiffany DeSouza…·Silvia Corvera
The paper identifies a neurogenic signature involving MAOA that controls human thermogenic adipose tissue development and shows its therapeutic potential for metabolic disease.