Author

Peter F. Leadlay

University of CambridgeORCID 0000-0002-3247-509XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:zebrafish· 1

Frequent Co-Authors

Cheng WangiD· 1 shared Chengbing Qiu· 1 shared Chuan HuangiD· 1 shared Dong LiuiD· 1 shared Fuling ZhouiD· 1 shared Guo Sun· 1 shared Shijuan WuiD· 1 shared Xinyun JianiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Cheng WangORCID

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1 paper

Recent·Most cited

Synthetic BiologyActa Pharmaceutica Sinica BPeer-reviewedMay 3, 2024

Glycodiversification of gentamicins through in vivo glycosyltransferase swapping enabled the creation of novel hybrid aminoglycoside antibiotics with potent activity and low ototoxicity

Xinyun Jian, Cheng Wang, Shijuan Wu…·Yuhui Sun

This study creates novel hybrid aminoglycoside antibiotics by swapping glycosyltransferases between gentamicin and kanamycin producers, resulting in compounds with potent activity and reduced ototoxicity.

17 citationstop 4%

zebrafishexperimental assay

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