This study investigates how CB1 receptor deletion in prefrontal GABAergic neurons affects emotional and cognitive processes differently in male and female mice.

bioRxiv · Jul 27, 2026 · PreprintNeuroscience

Astrocytic morphology in the Medial Habenula: sex differences and modulatory factors

Cathaysa Rodríguez-Cedrés, Lucía Sangroniz-Beltrán, Nahia López De Murga, Naroe Delgado-Martin, Goiane Andueza-Peral, Paula Mugica-Susaeta, Eva‐Gunnel Ducourneau, Paula Ospital, Sandra Beriain, María Ceprián, Jon Egaña Huguet, Joaquín Piriz, Guillaume Ferreira, Susana Mato, Edgar Soria Gómez

This study examines sex-dependent astrocytic morphology in the medial habenula and its modulation by metabolic and inflammatory factors.

bioRxiv · Jul 2, 2026 · PreprintNeuroscience

NEUROGLIAL CB1 RECEPTORS CONTROL NAVIGATION STRATEGIES

Jon Egaña Huguet, Lucía Sangroniz-Beltrán, Andrés M. Baraibar, Pablo Alejandro Reyes-Velásquez, Nicolas F. Landgraf, Paula Torres-Maldonado, Cathaysa Rodríguez-Cedrés, Francisca Julio‐Kalajzić, Joaquín Piriz, Almudena Ramos, Pedro Grandes, Giovanni Marsicano, Susana Mato, María Ceprián, Edgar Soria Gómez

This study shows that CB1 receptors in neurons and astrocytes differentially affect spatial navigation and memory in male and female mice.

bioRxiv · May 27, 2025 · PreprintNeuroscience