Edgar Soria Gómez

This study investigates how CB1 receptor deletion in prefrontal GABAergic neurons affects emotional and cognitive processes differently in male and female mice.

This study examines sex-dependent astrocytic morphology in the medial habenula and its modulation by metabolic and inflammatory factors.

This study develops a mouse model of locus coeruleus alpha-synuclein overexpression to investigate early Parkinson's disease features, finding functional and neurochemical disruptions without neuronal loss.

The paper analyzes bursting patterns in Lateral Habenula neurons using experimental data and a computational model, identifying distinct dynamic states and their implications for mood regulation.

This study identifies MYRF dysregulation as a mechanism linking Aβ pathology to oligodendrocyte and cognitive impairments in Alzheimer's disease, showing that PKC inhibition can restore myelin and cognition.

This study shows that CB1 receptors in neurons and astrocytes differentially affect spatial navigation and memory in male and female mice.

This study identifies aberrant astrocytic calcium signaling in MS models as a contributor to synaptic plasticity impairment and gray matter pathology.

The paper generates and characterizes a mutant mouse lacking mitochondrial-associated CB1 receptors to study their role in brain function and drug effects.

The paper identifies a circuit involving endocannabinoid modulation of excitatory projections from the anterior cingulate cortex to the basolateral amygdala that promotes water intake.

This study identifies a specific subclass of hippocampal interneurons that regulate recognition memory consolidation through CB1 receptor signaling and GABAergic inhibition.