Rishi Das Roy

broadSeq benchmarks differential gene expression methods and shows DELocal identifies distinct genes by considering genomic neighbourhood, particularly for highly expressed genes.

The paper shows antibiotic history shapes microbial response through eco-evolutionary and environmental feedbacks, creating a trade-off between resistance and recovery.

The paper investigates how mammalian molar teeth scale during development and evolution, finding that the IGF pathway regulates both growth and cusp patterning to achieve size differences.

The paper uses bulk and single-cell transcriptomics to study early hair follicle and epidermal development, identifying new cell populations and markers.

The paper introduces DELocal, an algorithm that uses gene neighbourhood information to detect subtle changes in gene expression during organ development, showing it outperforms traditional methods.

The paper identifies developmental keystone genes in mouse and rat tooth development by analyzing phenotypic severity and gene expression patterns, revealing conserved system-level dynamics.