Author

Sebastian Stintzing

German Cancer Research CenterORCID 0000-0002-3297-5801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Amina HasanovićiD· 1 shared Bettina Mundt· 1 shared Bjoern PapkeiD· 1 shared Cédric Moris· 1 shared Damian Tobias RiekeiD· 1 shared David Horst· 1 shared Elena Ioana BraicuiD· 1 shared Emil Netz· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Amina HasanovićORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 25, 2026

Copy number signatures in targeted gene panels associate with patient outcomes in routine clinical data

Emil Netz, Cédric Moris, Amina Hasanović…·Frank P. B. Dubois

The paper shows that copy number signatures from targeted gene panels are clinically relevant and associated with patient outcomes in ovarian, pancreatic, and colorectal cancers.

DOI 10.64898/2026.09.20.752979

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCell Death and DifferentiationPeer-reviewedApr 9, 2025

Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition

Tamara Isermann, Kim Lucia Schneider, Florian Wegwitz…·Ramona Schulz‐Heddergott

This study shows that combining HSP90 inhibitors with p53 activation or CDK4/6 inhibition enhances colorectal cancer therapy by disrupting the HSF1-HSR feedback loop.

19 citationstop 4%

mousehuman

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