Pharmacology & ToxicologybioRxivPreprint
Structural and Functional Characterization of the KCNJ6 G154C Variant Reveals Severe GIRK2 Channel Gain-of-Function and Opportunities for Drug Repurposing
Michael A. Netzer, Ilya Steshin, Theres Friesacher…·Anna Stary‐Weinzinger
The paper characterizes a KCNJ6 G154C variant, revealing its severe gain-of-function in GIRK2 channels and identifies drug candidates for treatment.
DOI 10.64898/2026.07.28.741201