Author

Anna Stary‐Weinzinger

University of ViennaORCID 0000-0002-9202-0484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 3 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Assay:electrophysiology· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Nathan DascaliD· 3 shared Theres FriesacheriD· 3 shared Boris ShalomoviD· 2 shared Daniel YakubovichiD· 2 shared Haritha P. ReddyiD· 2 shared Attila KissiD· 1 shared Bruno Karl PodesseriD· 1 shared CARMEN W. DESSAUERiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPharmacology & Toxicology

Nathan DascalORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural and Functional Characterization of the KCNJ6 G154C Variant Reveals Severe GIRK2 Channel Gain-of-Function and Opportunities for Drug Repurposing

Michael A. Netzer, Ilya Steshin, Theres Friesacher, Nathan Dascal, Anna Stary‐Weinzinger

The paper characterizes a KCNJ6 G154C variant, revealing its severe gain-of-function in GIRK2 channels and identifies drug candidates for treatment.

bioRxiv · Jul 31, 2026 · PreprintPharmacology & Toxicology

Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels

Reem Handklo‐Jamal, Tal Keren Raifman, Boris Shalomov, Patrick Hofer, Uri Kahanovitch, Theres Friesacher, Galit Tabak, Vladimir Tsemakhovich, Haritha P. Reddy, Orna Chomsky-Hecht, Debi Ranjan Tripathy, Kerstin Zühlke, CARMEN W. DESSAUER, Enno Klußmann, Yoni Haitin, , Nathan Dascal

The paper shows Gβγ interacts with GIRK2 and GIRK1/2 channels with affinities in the microM range, with GIRK1/2 having higher apparent affinity due to a unique Gβγ docking site.

Nature Communications · Nov 24, 2025Peer-reviewedPhysiology

The sodium/glucose cotransporter 2 inhibitor empagliflozin is a pharmacological chaperone of cardiac Nav1.5 channels

Jakob Sauer, Jessica Marksteiner, Martin HOHENEGGER, Hannes Todt, Helmut Kubista, Christopher Dostal, Attila Kiss, Bruno Karl Podesser, Isabella Salzer, Xaver Koenig, Anna Stary‐Weinzinger, Karlheinz Hilber, Oliver Kudlacek

This study shows empagliflozin enhances peak sodium current in Nav1.5 channels by acting as a pharmacological chaperone, potentially reducing arrhythmia risk in Duchenne muscular dystrophy.

American Journal of Physiology-Heart and Circulatory Physiology · Aug 13, 2025Peer-reviewedPharmacology & Toxicology

Ethosuximide: subunit- and Gβγ-dependent blocker and reporter of allosteric changes in GIRK channels

Boris Shalomov, Theres Friesacher, Daniel Yakubovich, John Carlo Combista, Haritha P. Reddy, Shoham Dabbah, Harald Bernsteiner, Eva‐Maria Zangerl‐Plessl, Anna Stary‐Weinzinger, Nathan Dascal

This study identifies ethosuximide as a subunit-selective, Gβγ-dependent blocker of GIRK channels, revealing its mechanism of action and potential as a therapeutic tool.

British Journal of Pharmacology · Jan 15, 2025Peer-reviewedPharmacology & Toxicology