Author

Linnaea E. Ostroff

University of ConnecticutORCID 0000-0002-3348-342XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Zachary DeaneiD· 3 shared Eric KlanniD· 2 shared Janeth Pérez-GarzaiD· 2 shared Joseph E. LeDouxiD· 2 shared Adriana HeguyiD· 1 shared Aristotelis TsirigosiD· 1 shared Benjamin W. BotsfordiD· 1 shared Charles A. HoefferiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Zachary DeaneORCID

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Author profile →

4 papers

Recent·Most cited

Ultraplex microscopy: versatile highly-multiplexed molecular labeling and imaging across scale and resolution

Janeth Pérez-Garza, Jairo Orea, Zachary Deane, Gianna M. Raimondi, Rebecca Tripp, Imani Charles, Linnaea E. Ostroff

This paper introduces ultraplex microscopy, a method that enables highly multiplexed molecular labeling and imaging across different resolutions and modalities.

bioRxiv · Aug 17, 2024 · PreprintNeuroscience

Rehydration of freeze substituted brain tissue for preembedding immuno-electron microscopy

Janeth Pérez-Garza, Emily Parrish-Mulliken, Zachary Deane, Linnaea E. Ostroff

This paper introduces a method for rehydrating freeze-substituted brain tissue to enable immunolabeling while preserving ultrastructure for electron microscopy.

Microscopy and Microanalysis · Jul 19, 2023Peer-reviewedNeuroscience

Upregulation of eIF4E, but not other translation initiation factors, in dendritic spines during memory consolidation

Sofya Gindina, Benjamin W. Botsford, Kiriana K. Cowansage, Joseph E. LeDoux, Eric Klann, Charles A. Hoeffer, Linnaea E. Ostroff

The Journal of Comparative Neurology · Apr 17, 2021Peer-reviewedNeuroscience

The translatome of adult cortical axons is regulated by learning in vivo

Linnaea E. Ostroff, Emanuela Santini, Robert M. Sears, Zachary Deane, Joseph E. LeDoux, Tenzin W. Lhakhang, Aristotelis Tsirigos, Adriana Heguy, Eric Klann

The paper shows that learning regulates protein synthesis in adult rat amygdala axons, identified through TRAP-RNASeq, revealing upregulated mitochondrial and translation-related genes and downregulated synaptic genes.

bioRxiv · Jan 4, 2019 · PreprintNeuroscience