Author

Guillermo Carbajosa

King's College LondonORCID 0000-0002-3374-0895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Angela HodgesiD· 2 shared Charles A. MeiniD· 2 shared David Andrew CollieriD· 2 shared Eva L. WoźniakiD· 2 shared Hong WangiD· 2 shared John W. RyderiD· 2 shared Karim MalkiiD· 2 shared Kristie Wood· 2 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Angela HodgesORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TREM2 impacts brain microglia, oligodendrocytes and endothelial co-expression modules revealing genes and pathways important in Alzheimer s disease

Guillermo Carbajosa, Karim Malki, Nathan Lawless, Hong Wang, John W. Ryder, Eva L. Woźniak, Kristie Wood, Charles A. Mein, Alan Hodgkinson, Richard Dobson, David Andrew Collier, Michael J. O’Neill, Stephen Newhouse, Angela Hodges

This study identifies TREM2-dependent genes and pathways in Alzheimer's disease by analyzing RNA sequencing data from brain samples, revealing its impact on microglia, oligodendrocytes, and endothelial cells.

bioRxiv · Jul 16, 2021 · PreprintNeuroscience

Loss of Trem2 in microglia leads to widespread disruption of cell co-expression networks in mouse brain

Guillermo Carbajosa, Karim Malki, Nathan Lawless, Hong Wang, John W. Ryder, Eva L. Woźniak, Kristie Wood, Charles A. Mein, Richard Dobson, David Andrew Collier, Michael J. O’Neill, Angela Hodges, Stephen Newhouse

This study examines the transcriptional effects of Trem2 loss in mouse brain, revealing disruptions in cell co-expression networks and highlighting a potential role for Trem2 in endothelial cell homeostasis.

Neurobiology of Aging · May 17, 2018Peer-reviewedSystems Biology