Author

Shaowei Li

ShanghaiTech UniversityORCID 0000-0002-3374-1038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Airu ZhuiD· 1 shared Banghui LiuiD· 1 shared Canjie Chen· 1 shared Chuanying Niu· 1 shared Dinghui WuiD· 1 shared Fandi WuiD· 1 shared Fangli Chen· 1 shared Hai Jing YuiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Airu ZhuORCID

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2 papers

Recent·Most cited

AI recognizes convergent somatic hypermutation signatures to allow the discovery of variant-resilient broadly neutralizing antibodies

Qihong Yan, Xiaohan Huang, Banghui Liu, Yicheng Yao, Huiran Zheng, Yidong Song, Fandi Wu, Zhiyun He, Shaowei Li, Fangli Chen, Chuanying Niu, Zimu Li, Hang Yuan, Yuting Lin, Lan Chen, , Jincun Zhao

The paper uses AI to identify convergent somatic hypermutation patterns in antibodies, enabling the discovery of variant-resilient broadly neutralizing antibodies from early-pandemic data.

bioRxiv · Dec 12, 2025 · PreprintImmunology

Characterization of the SARS-CoV-2 Spike in an Early Prefusion Conformation

Tingting Li, Qingbing Zheng, Hai Jing Yu, Dinghui Wu, Wenhui Xue, Yuyun Zhang, Xiaofen Huang, Lizhi Zhou, Zhigang Zhang, Zhenghui Zha, Tingting Chen, Zhiping Wang, Jie Chen, Hui Sun, Tingting Deng, , Ningshao Xia

The paper characterizes an early prefusion conformation of the SARS-CoV-2 Spike protein using cryo-EM and shows it forms a homotrimer with significant glycosylation.

bioRxiv · Mar 16, 2020 · PreprintMolecular Biology