Author

Yicheng Yao

Sun Yat-sen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Banghui LiuiD· 2 shared Chuanying Niu· 2 shared Fandi WuiD· 2 shared Hang YuaniD· 2 shared Huiran Zheng· 2 shared Jianhua YaoiD· 2 shared Jincun ZhaoiD· 2 shared Qihong YaniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Banghui LiuORCID

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Author profile →

2 papers

Recent·Most cited

Structural determinants of IGHV1-69 public antibodies conferring resilience to SARS-CoV-2 antigenic escape

Chuanying Niu, Xiaohan Huang, Qihong Yan, Banghui Liu, Xijie Gao, Yidong Song, J. Y. Wang, Longyu Wang, Zimu Li, Huiran Zheng, Ping He, Xiaodong Huang, Hang Yuan, Binqian Zou, Yuedong Yang, , Xiaoli Xiong

This study identifies structural features of affinity-matured R1-32-like antibodies that enable tolerance to SARS-CoV-2 mutations and reveals an ultrapotent antibody with broad variant activity.

bioRxiv · Mar 23, 2026 · PreprintImmunology

AI recognizes convergent somatic hypermutation signatures to allow the discovery of variant-resilient broadly neutralizing antibodies

Qihong Yan, Xiaohan Huang, Banghui Liu, Yicheng Yao, Huiran Zheng, Yidong Song, Fandi Wu, Zhiyun He, Shaowei Li, Fangli Chen, Chuanying Niu, Zimu Li, Hang Yuan, Yuting Lin, Lan Chen, , Jincun Zhao

The paper uses AI to identify convergent somatic hypermutation patterns in antibodies, enabling the discovery of variant-resilient broadly neutralizing antibodies from early-pandemic data.

bioRxiv · Dec 12, 2025 · PreprintImmunology