Cancer BiologybioRxivPreprint
Quantitative and sensitive neuroblastoma minimal residual disease detection using extrachromosomal DNA (ecDNA) breakpoints
Annabell Szymansky, Falk Hertwig, Annika Winkler…·Johannes Hubertus Schulte
This study develops a method to detect minimal residual disease in neuroblastoma using ecDNA breakpoints, achieving high sensitivity and specificity in bone marrow samples.
DOI 10.64898/2026.09.06.749680