Author

Barbara Hero

University Hospital CologneORCID 0000-0003-4129-890XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Anton George HensseniD· 2 shared Bastiaan SpanjaardiD· 2 shared Nadine WittstruckiD· 2 shared Richard P. KocheiD· 2 shared Aditi GnanasekariD· 1 shared Alastair Hamilton· 1 shared Alexander Herrmann· 1 shared Alexander KukaleviD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Anton George HenssenORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 12, 2026

Quantitative and sensitive neuroblastoma minimal residual disease detection using extrachromosomal DNA (ecDNA) breakpoints

Annabell Szymansky, Falk Hertwig, Annika Winkler…·Johannes Hubertus Schulte

This study develops a method to detect minimal residual disease in neuroblastoma using ecDNA breakpoints, achieving high sensitivity and specificity in bone marrow samples.

DOI 10.64898/2026.09.06.749680

humanwhole-genome sequencing

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Cancer BiologybioRxivPreprintApr 15, 2025

Extrachromosomal DNA micronucleation constrains tumour fitness andimproves patient survival

Lotte Brückner, Robin Xu, Jun Tang…·Anton George Henssen

This study shows that ecDNA mis-segregation leads to micronuclei formation, reduced oncogene transcription, and improved patient survival in neuroblastoma.

7 citations

humanexperimental assay

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