Author

Simon Hendrik Stitzinger

Max Planck Institute for Multidisciplinary SciencesORCID 0000-0002-3400-1461Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreas JanshoffiD· 1 shared Argyris PapantonisiD· 1 shared Carmelo FerraiiD· 1 shared Carsten SchulteiD· 1 shared Claudio PiazzoniiD· 1 shared Eirini KalogerakouiD· 1 shared Eugenio F. FornasieroiD· 1 shared Ibrahim I. CisséiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Andreas JanshoffORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 13, 2026

The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A

Yomna Gohar, Eirini Kalogerakou, Matthias Akyel…·Carmelo Ferrai

This study shows that nanotopography regulates pluripotency in mESCs by altering chromatin state through the mechanosensitive demethylase KDM3A.

DOI 10.64898/2026.02.12.705261

mousebulk RNA-seq

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Molecular BiologyNAR Genomics and BioinformaticsPeer-reviewedJun 1, 2022

Cooperativity boosts affinity and specificity of proteins with multiple RNA-binding domains

Simon Hendrik Stitzinger, Salma Sohrabi-Jahromi, Johannes Söding

The paper develops a thermodynamic model to predict binding affinity of multi-domain RNA-binding proteins, showing how cooperativity enhances specificity and affinity beyond individual domains.

22 citations

statistical model

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