Andreas Janshoff

Probing the Mechanical Properties of Pore-Spanning Plasma Membranes via AFM Indentation

This study quantitatively characterizes the mechanical properties of isolated plasma membranes using AFM indentation, revealing distinct pre-tension and compressibility compared to artificial membranes.

Myosin activity drives entangled actin networks out-of-equilibrium - a quantitative approach

This paper quantifies how ATP concentration modulates nonequilibrium fluctuations in reconstituted actomyosin networks using mean back relaxation analysis.

The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A

This study shows that nanotopography regulates pluripotency in mESCs by altering chromatin state through the mechanosensitive demethylase KDM3A.

Membrane curvature regulates Ups1 dependent phosphatidic acid transfer across lipid bilayers

The paper shows Ups1 preferentially binds to positively curved membranes, facilitating phosphatidic acid transfer between mitochondrial membranes.

Epithelial polarity drives tissue tension in planar, free standing cell monolayers

This study examines how epithelial cell polarity affects tissue tension in free-standing monolayers, showing that basal cortex tension drives elastic responses while apical regions exhibit hysteresis.

Mechanical Implications of Cellular Viscoelasticity, Cortex Polarity, Superelasticity, and Cell-Cell Junctions in Curved Tissues

The paper investigates how mechanical properties of curved epithelial tissues respond to deformation, identifying factors like viscoelasticity and cell-cell junctions that influence tissue behavior.

The Keratin Cortex Stabilizes Cells at High Strains

This study investigates the mechanical role of keratin cortex in epithelial cells by comparing keratin-deficient and wild-type cells under strain.

Cell-substrate distance fluctuations of confluent cells enable fast and coherent collective migration

The paper examines how cell-substrate distance fluctuations affect collective migration in confluent monolayers of MDCKII cells and their ZO1/2-depleted variants.