Juan Camilo Nieto

This study presents the first comprehensive single-cell and multi-omic atlas of pleural effusions, revealing disease-specific immune landscapes and tumor heterogeneity.

STAMP enables low-cost, high-throughput single-cell analysis by integrating transcriptomics and proteomics imaging, supporting both single and multimodal profiling of diverse cell types.

This study tracks T cell dynamics in a pediatric cancer patient post-ICI therapy to identify tumor-reactive TCRs for personalized TCR-T cell therapy.

The paper uses single-cell sequencing and spatial transcriptomics to compare immune responses in leptomeningeal disease with other CNS disorders, identifying disease-specific immune environments and progression mechanisms.

FixNCut is a reversible fixation and dissociation method that preserves RNA integrity and cellular composition in human and mouse tissues, enabling robust single-cell and spatial analyses.