Jennifer A. Crodelle

Mechanisms for dysregulation of excitatory-inhibitory balance underlying allodynia in dorsal horn neural subcircuits

This paper identifies mechanisms of excitatory-inhibitory balance dysregulation in spinal cord dorsal horn subcircuits that contribute to allodynia, revealing subcircuit-specific vulnerabilities and potential therapeutic targets.

Biophysical Modeling and Experimental Analysis of the Dynamics of C. elegans Body-Wall Muscle Cells

This paper develops a biophysically detailed model of C. elegans body-wall muscle cells using experimental data and a simulation-based inference method to estimate parameters and validate the model's accuracy.

Idealized model of the developing visual cortex

This paper constructs an idealized model of the developing mouse visual cortex to study the role of gap-junction coupling in synaptic plasticity and orientation preference map formation.

Investigating circadian rhythmicity in pain sensitivity using a neural circuit model for spinal cord processing of pain

The paper develops a neural circuit model of spinal cord pain processing to investigate circadian rhythmicity in pain sensitivity and identifies dysregulated inhibition as a mechanism for phase shifts in neuropathic pain.

The Modulation of Pain by Circadian and Sleep-Dependent Processes: A Review of the Experimental Evidence

This paper reviews experimental evidence on how circadian rhythms and sleep affect pain sensitivity, informing mathematical models of pain-sleep interactions.